HOT - Botox as a Treatment for Depression

A new study to be published in the May issue of The Journal of Psychiatric Research finds that it may be possible to treat depression with Botox injections, which prevent patients from frowning.

botox treatment
Seventy-four patients with major depression were randomly assigned to receive either a Botox or placebo saline injection in a double-blind trial. (While there is evidence that the blind was at least partially breached, surprisingly only about half of the patients who received Botox injections guessed correctly. Furthermore, a patient's ability to discern which injection he or she received had no significant effect on treatment response.) Six weeks after the injection, 52 percent of the subjects who received Botox exhibited relief from depression, compared with only 15 percent of those who got the saline injection.

The idea that our facial expressions can enhance, perhaps even create, emotional responses isn’t new (Charles Darwin proposed the theory of “facial feedback hypothesis” way back in 1872: “The free expression by outward signs of an emotion intensi­fies it,” he wrote). Neither is the theory that, by inhibiting one's ability to frown, Botox can improve one's mood. Back in 2008, psychologists at the University of Cardiff in Wales provided an anxiety and depression questionnaire to 25 women, half of whom had received Botox injections. While those who received the Botox didn't say they felt any more attractive than they had before the injection, they did report feeling less anxious and happier (suggesting that Botox's ability to boost one's mood can't simply be attributed to its ability to boost one's appearance).

There are many reasons, the authors of the study to be published in The Journal of Psychiatric Research speculate, why Botox may help alleviate the symptoms of depression. "First, frowning may affect the way people feel about themselves when they look in the mirror and the way others respond to them," they write; Eliminating a person's ability to grimace will logically cause them to interact more positively with those around them, boosting their mood.

Finally, and most dramatically, the authors hypothesize that the act of frowning in itself may be a depressant. In other words, our brain monitors "the extent of our facial muscle contraction and muscle tension" (i.e.our facial expressions) and adjusts our mood accordingly; Muscles tensed up into a grimace will cause the brain to generate the corresponding emotional experience. Botox treatment, the authors predict, "would interrupt the normal circuitry, reduce distress signals to the brain and thereby influence mood in a favorable way."

Botox or no Botox, the study illustrates that our facial expressions are important. Choosing to give into our dismal mood and frown – instead of smiling through any internal unpleasantness – may impact our ability to adopt a sunnier outlook.

Not only that, but our emotions are highly contagious. Because we tend to mimic the behavior of those around us, we are highly susceptible to "catching" each other's' moods. Both negative and positive emotion can spread through an office much like a cold does.

Maybe the solution is Botox for everyone. Or perhaps it's simply to heed the advice we all got (and rolled our eyes at) as children. The next time you face a rainy Monday commute, go ahead and try it: Turn that frown upside down and see what happens.

Top 10 Vegetables For Health and Beauty

Veggies are an important part of everyone's diet. They contain dozens of important nutrients and have loads of dietary fiber. And just by getting your daily quota of five to nine servings, you help build your body's immunity to things like cancer, heart disease and diabetes. So what are the top veggies you should be eating to boost your disease-fighting potential? Read on to find out.

Tomatoes

tomatoes

Though technically a fruit, tomatoes are most often served like a vegetable. Full of lycopene, these beautiful red orbs (and all tomato-based products) are renowned for their cancer-fighting capabilities. Not only are they chock full of vitaminy goodness (from vitamins A to K), they also keep our blood pressure in check and help to reduce the number of free radicals in our bodies.

Broccoli

brocolli

Few foods measure up to the disease-fighting potential of broccoli. This cruciferous veg is packed with antioxidants that help reduce the risk of stomach, lung and rectal cancers. And because broccoli is rich in beta-carotene, vitamin C and folate, it is also good at boosting your immunity to colds and flus.

Brussels sprouts


brussels sprouts

These little green veggies are especially important for pregnant woman because they're packed with folic acid, a B-vitamin that prevents neural tube defects. Brussels sprouts are also packed with vitamins C and K as well as fiber, potassium and omega-3 fatty acids.

Carrots

carrots

These orange-wonders are loaded with eye, skin and hair-enriching nutrients. They're also the richest vegetable source of some important antioxidants, like vitamin A. And because they're rich in vitamin C, carrots protect your cardiovascular system from damage.

Squash

squash

A good source of anti-inflammatory nutrients like vitamin C and beta-carotene, squash, especially summer squash, can help treat dozens of conditions including asthma, osteoarthritis and rheumatoid arthritis. Squash is also rich in potassium, magnesium and fiber.

Sweet potato

potatoes

This root vegetable has dozens of anti-cancer nutrients like vitamin A, C and manganese. They're also a good source of fiber and iron, so not only do they give you energy, they can also help regulate your digestive system.

Eggplant

eggplant

High in heart healthy nutrients, eggplants are rich in antioxidants like nasunin (a unique compound that protects your brain cells from damage). And because eggplants are loaded with fiber and potassium, researchers believe they may reduce your risk of stroke and dementia.

Bell Peppers

peppers

Whether you prefer red, orange or yellow, bell peppers are packed with dozens of heart-healthy nutrients like lycopene and folic acid. And recent research suggests digging into a pepper every day may lower your risk of developing lung, colon, bladder and pancreatic cancers.

Spinach

spinach

This chlorophyll-packed type of produce is an excellent source of almost every vitamin and nutrient you need.
Scientists believe a diet heavy in spinach may be able to prevent everything from heart disease to colon cancer, and arthritis to osteoporosis.

Onions

onions

These pungent smelling veggies are particularly good for people suffering from (or at risk of developing) osteoporosis. That's because onions are loaded with a peptide called GPCS which scientists believe slows your body's loss of calcium. Onions may also be useful in the fight against heart disease and diabetes because they're loaded with vitamin C and folate.